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Intrinsic factor

Definition

Intrinsic factor is a protein produced by glands in the stomach lining. It is needed for the intestines to absorb vitamin B12.

A lack (deficiency) of enough intrinsic factor can cause pernicious anemia. Such deficiencies can be caused by surgical removal of the stomach, inherited conditions, or other diseases.

Review Date: 2007-05-17
Reviewed By: Benjamin W. Van Voorhees, M.D., M.P.H., Assistant Professor of Medicine, Pediatrics, and Psychiatry, The University of Chicago, Chicago, IL. Review provided by VeriMed Healthcare Network.
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