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Trigeminal neuralgia

Definition

Trigeminal neuralgia is an extremely painful inflammation of the largest nerve in the skull (trigeminal nerve).

Alternative Names

Tic douloureux

Causes, incidence, and risk factors

Trigeminal neuralgia causes severe lightening-like facial pain on the side of the affected nerve. The condition usually affects older adults. Often, no cause can be found, although areas of brain inflammation or abnormal blood vessels (arteriovenous malformations) can be responsible.

Painful trigeminal neuralgia attacks may occur after lightly touching different skin areas of the face, along the course of the sixth cranial (skull) nerve.

Symptoms

  • Very painful, sharp electric-like spasms last a few seconds to minutes
  • Pain is triggered by touch or sounds
  • Pain during chewing, eating, drinking, shaving, or brushing teeth

Signs and tests

An MRI and blood tests may help rule out other conditions.

Treatment

Certain medicines can help reduce pain and the rate of attacks. Medicines may include:

  • Anti-epilepsy drugs
  • Migraine medicines (sumatriptan)
  • Tricyclic antidepressants such as amitriptyline, nortriptyline, or carbamazepine

Some patients may require surgery. 

References

Kanai A, Saito M, Hoka S. Subcutaneous sumatriptan for refractory trigeminal neuralgia. Headache. 2006 Apr;46(4):577-82.

Goetz, CG. Textbook of Clinical Neurology. 2nd ed. St. Louis, Mo: WB Saunders; 2003: 178-179.

Review Date: 2006-04-28
Reviewed By: Daniel Kantor, M.D., Director of the Comprehensive MS Center, Neuroscience Institute, University of Florida Health Science Center, Jacksonville, FL. Review provided by VeriMed Healthcare Network.
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The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © HealthProfessor LLC. Any duplication or distribution of the information contained herein is strictly prohibited.